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1- Assistant Professor, Department of Forensic Medicine, Jorhat Medical College and Hospital, Jorhat, Assam, India , dipankar.fmt@gmail.com
2- Post Graduate Trainee, Department of Pathology, Jorhat Medical College and Hospital, Jorhat, Assam, India
3- Professor and HOD, Department of Pathology, Jorhat Medical College and Hospital, Jorhat, Assam, India
4- Associate Professor, Department of Pathology, Jorhat Medical College and Hospital, Jorhat, Assam, India
Abstract:   (125 Views)
Background: Pathological autopsy plays a crucial role in understanding mortality causes, especially in cases where diagnosis during life was incomplete or impossible. The collaboration between forensic experts and pathologists provides valuable insights into the cause and manner of death. Aim: The study aimed to determine the prevalence and pattern of lung, liver, and kidney histopathology, assess demographic associations, and investigate etiological factors contributing to these pathologies. Methods: A retrospective, non-interventional, record based cross sectional study was conducted for a period of five years from 1st January 2019 to 31st December 2023, analyzing 90 autopsy cases excluding decomposed bodies and cases primarily due to extensive trauma. Results: Lung pathology was observed in 61.1% of cases, predominantly showing congestion and inflammation. Liver diseases were found in 47.7% of cases, with steatosis and cirrhosis notable, especially among males. Kidney pathology was present in 50% of cases, with various changes noted. Demographic distribution indicated a higher prevalence among males, with sudden death, chronic alcohol abuse, and road traffic accidents being common causes. Conclusion: The study emphasizes the significant burden of lung, liver, and kidney pathology in autopsy cases, particularly among males, highlighting the importance of autopsy in understanding the underlying causes of death and guiding public health interventions and forensic investigations.
Full-Text [PDF 849 kb]   (38 Downloads)    
Research Article: Research Article | Subject: Pathology
Received: 2024/05/7 | Accepted: 2025/02/24

References
1. Kotabagi RB, Charati SC, Jayachandar D. Review article clinical autopsy vs medicolegal autopsy. Med J Armed Forces India. 2005;61(3):258-63. [View at Publisher] [DOI] [PMID] [Google Scholar]
2. Khare P, Gupta R, Ahuja M, Khare N, Agarwal S, Bansal D. Prevalence of lung lesions at autopsy: A histopathological study. J Clin Diagn Res. 2017;11(5):EC13-6. [View at Publisher] [DOI] [PMID] [Google Scholar]
3. Garg P, Sharma A, Kundal RK. Spectrum of pulmonary histopathological lesions: A study of 100 autopsy cases.J Med Sci Clin Res. 2017;5(12):31305-6. [View at Publisher] [DOI] [Google Scholar]
4. Kurawar RR, Vasaikar MS. Spectrum of histomorphological changes in lungs at autopsy: A 5 year study. Annals Pathol Lab Med. 2017;1(1):31304-8. [View at Publisher] [DOI] [Google Scholar]
5. Selvambigai G, Amudhavalli S, Deepak Chakravarthi CD,Ravi S. Histopathological study of lung in autopsy cases: A prospective study. Int J Res Med Sci. 2016;4(11):4816-9. [View at Publisher] [DOI] [Google Scholar]
6. Kumar V, Abbas AK, Aster JC. Robbins and Cotran Pathologic Basis of Disease. 10th ed. London: Churchill Livingstone, Elsevier; 2017. [View at Publisher] [Google Scholar]
7. Bal MS, Singh SP, Bodal VK, Oberoi SS, Surinder K. Pathological findings in liver autopsy. J Indian Acad Forensic Med. 2004;26(2):97-101. [View at Publisher] [DOI] [Google Scholar]
8. Sotoudehamanesh R, Sotoudeh M, Asgari A, Abedi-Ardakani B, Tavangar SM, Khakinejad A, et al. Silent liver diseases in autopsies from forensic medicine of Tehran. Arch Iran Med. 2006;9(4):324-8. [View at Publisher] [PMID] [Google Scholar]
9. Fubara DS, Jebbin NJ. Hepatocellular carcinoma in Port Harcourt, Nigeria: clinicopathologic study of 75 cases. Ann Afr Med. 2007;6(2):54-7. [View at Publisher] [DOI] [PMID] [Google Scholar]
10. Selvi RT, Selvam V, Subramanium PM. Common silent liver diseases in and around Salem population: an autopsy study. J Clin Diagn Res. 2012;6(2):207-10. [View at Publisher] [Google Scholar]
11. Merat S, Sotoudehmanesh R, Nouraie M, Peikan-Heirati M, Sepanlou SG, Malekzadeh R, et al. Sampling error in histopathology findings of non-alcoholic fatty liver diseases: a postmortem liver histology study. Arch Iran Med. 2012;15(7):418-20. [View at Publisher] [PMID] [Google Scholar]
12. Voinova LV. Aetiological and nosological structure of liver diseases (on autopsy data of clinics of I.M. Sechenov Moscow Medical Academy in 1988-1997). Arkh patol. 2000;62(2):45-7. [View at Publisher] [PMID] [Google Scholar]
13. Umesh BR, Gayathri BN, Harendra Kumar ML. Spectrum of liver pathology at autopsy. Int J Res Rev. 2015;2(3):79-86. [View at Publisher]
14. Devi PM, Myrthong BG, Meera T, Nabachandra H. Pathological findings of liver in autopsy cases: A study at Imphal. J Indian Acad Forensic Med. 2013;35(3):206-10. [View at Publisher] [DOI] [Google Scholar]
15. Berry CL. Liver lesions in an autopsy population. Hum Toxicol. 1987;6(3):209-14. [View at Publisher] [DOI] [PMID] [Google Scholar]
16. Pudale SS, Ashok BS, Ambadas PG, Gajanan DR, Pandharinath CN. Study of liver pathology in autopsy cases. Int J Curr Res. 2014;6(3):5795-97. [Google Scholar]
17. Khare P, Gupta R, Agarwal S, Bhatnagar A, Anand R. Spectrum of Renal Lesions on Autopsy: Experience of a Tertiary Level Institute Based on Retrospective Histopathological Analysis. Cureus. 2021;13(8):e17064. [View at Publisher] [DOI] [Google Scholar]
18. Mulay PS, Khosla A. Kidney lesions in an autopsy: 3-year study in a tertiary health care hospital. J Med Sci Clin Res. 2020;8(2):878-83. [View at Publisher] [DOI] [Google Scholar]

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