Jorjani Biomedicine Journal

Backgrounds and Objectives: Afew large population-based studies have been conducted on the prevalence of oral mucosal lesions in relation to fertility status in the Iranian population. The aim of study was determine the prevalence of oral mucosal lesions in relation to fertility status in women participants of Shahedieh cohort study. 
Materials and Methods: A descriptive cross-sectional study was conducted on 4935 women who participated in the Shahedieh cohort study. The age range of participants was 35-71 years with a mean age of 47.12 years. The prevalence of oral mucosal lesions considering fertility variables including pregnancy, number of pregnancy, oophorectomy, tubectomy, hysterectomy, infertility, menopause, normal menopause, and abortion, application of infertility and oral contraceptive drugs and hormone replacement therapy were recorded.
 Results: The total prevalence of oral mucosal lesions in the studied women were 3.8%. The most commonly affected age group was 40-49 years, followed by 30-39, 50-59 and 60-71 years, respectively. Considering the fertility variables, only menopause (P=0.047) and normal menopause (P=0.024) significantly related to the prevalence of oral mucosal lesions.
Conclusions: The findings of the present study provide information on the prevalence of the oral mucosal lesions considering fertility status in a large population-based study in Iran. With due attention to the higher prevalence of oral mucosal lesions in menopause women, an improved comprehension of oral manifestations at menopause and preventive and treatment approaches during this period should be programmed with health care services to meet the needs of patients deservingly.
 

Background: Anabasis setifera and Caroxylon imbricatum are two halophytic and xerophytic plant species belonging to the family Chenopoodiaceae s.str., that are distributed widely in dry environments of the Old World. This study investigated the antioxidant and antibacterial properties of the hydroethanolic extracts of fruit-bearing branches of these species collected from Zabol in the east of Iran.
Methods: The antimicrobial effect was essayed using broth microdilution and streak plate protocols against nine pathogenic microorganisms from different genera, including Klebsiella, Pseudomonas, Escherichia, Bacillus, Staphylococcus, Streptococcus, Aspergillus, Fusarium and Candida. The antioxidant activity was measured by the DPPH free radical scavenging method.
Results: Extracts were effective on all tested bacterial and fungal strains except for Candida albicans, which Caroxylon imbricatum didn’t affect. The MIC values ranged from 8 to 2048 μg/ml. The IC₅₀ values of 76.40 and 154.05 μg/ml were observed with Anabasis setifera and Caroxylon imbricatum extracts, respectively.
Conclusion: These plant species can efficiently treat infectious and oxidative stress-related diseases due to their broad spectrum antimicrobial properties and acceptable antioxidant activities.